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Catalog No.:UPF020153

2,4,6-Trifluorobenzoic acid

  • 28314-80-9
CAS No.: 28314-80-9 Name:2,4,6-Trifluorobenzoic acid Purity: 98%
MF: C7H3F3O2 MW: 176.093
Synonyms: 2.4.6-Trifluorbenzoesaeure;2,4,6-triflluorobenzoic acid;2,4,6-F3C6H2COOH;2,3-DIHYDROXY NAPHTHALENE-6-SODIUM SULFONATE(DIHYDROXY R SALT);2,4,6-Trifluorobenzoicacid;2,4,6-Trifluorobenzioc acid;BENZOIC ACID,2,4,6-TRIFLUORO;2,4,6-Trifluorobenzoic Acid;
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2,4,6-Trifluorobenzoic acid



2,4,6-triflluorobenzoic acid;



2,4,6-Trifluorobenzioc acid;


2,4,6-Trifluorobenzoic Acid;

CAS No.:28314-80-9



Density:1.536 g/cm3

Boiling Point:218.2ºC at 760 mmHg

Melting Point:142-145 °C(lit.)

Flash Point: 85.7ºC

Refractive Index:1.49 



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According to the UN GHS revision 8

Version: 1.0

Creation Date: 2020-05-04

Revision Date: 2020-05-04

1.            Identification

               1.1                        GHS Product identifier

Product name

2,4,6-Trifluorobenzoic acid

               1.2                        Other means of identification

Product number


Other names

2.4.6-Trifluorbenzoesaeure;2,4,6-triflluorobenzoic acid;2,4,6-F3C6H2COOH;2,3-DIHYDROXY NAPHTHALENE-6-SODIUM SULFONATE(DIHYDROXY R SALT);2,4,6-Trifluorobenzoicacid;2,4,6-Trifluorobenzioc acid;BENZOIC ACID,2,4,6-TRIFLUORO;2,4,6-Trifluorobenzoic Acid;

               1.3                        Recommended use of the chemical and restrictions on use

Identified uses

For industry use only.

Uses advised against

no data available

               1.4                        Supplier's details


Shanghai Up-Fluorochem Co., Ltd.


T2-1623, Zhonggeng Global Creative Center, Lane 166, Minhong Road, Minhang District, Shanghai, China, 202155





1.5            Emergency phone number

Emergency phone number

Local Fire/Emergency Telephone Number

Service hours

Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

2.            Hazard identification

               2.1                        Classification of the substance or mixture

Skin irritation, Category 2

Eye irritation, Category 2

Specific target organ toxicity – single exposure, Category 3

               2.2                        GHS label elements, including precautionary statements

Signal word


Hazard statement(s)

H315 Causes skin irritation

H319 Causes serious eye irritation

H335 May cause respiratory irritation

Precautionary statement(s)

P264 Wash ... thoroughly after handling.

P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

P261 Avoid breathing dust/fume/gas/mist/vapours/spray.

P271 Use only outdoors or in a well-ventilated area.


P302+P352 IF ON SKIN: Wash with plenty of water/...

P321 Specific treatment (see ... on this label).

P332+P317 If skin irritation occurs: Get medical help.

P362+P364 Take off contaminated clothing and wash it before reuse.

P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P319 Get medical help if you feel unwell.


P403+P233 Store in a well-ventilated place. Keep container tightly closed.

P405 Store locked up.


P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

                2.3                        Other hazards which do not result in classification

no data available

3.            Composition/information on ingredients

               3.1                        Substances

Chemical nameCommon names and synonymsCAS numberEC numberConcentration
2,4,6-Trifluorobenzoic Acid2,4,6-Trifluorobenzoic acid2,4,6-Trifluorobenzoic acid 2,4,6-trifluorobenzoic acid2,4,6-Trifluorobenzoic Acid2,4,6-Trifluorobenzoic acid2,4,6-Trifluorobenzoic acid 2,4,6-trifluorobenzoic acid28314-80-9-98%

4.            First-aid measures

               4.1                        Description of necessary first-aid measures

General advice

Medical attention is required. Consult a doctor.                    Show this safety data sheet (SDS) to the doctor in attendance.

If inhaled

Move the victim into fresh air. If breathing is difficult, give oxygen. If not breathing, give artificial respiration and consult a doctor immediately. Do not use mouth to mouth resuscitation if the victim ingested or inhaled the chemical.

Following skin contact

Take off contaminated clothing immediately. Wash off with soap and plenty of water. Consult a doctor.

Following eye contact

Rinse with pure water for at least 15 minutes. Consult a doctor.

Following ingestion

Rinse mouth with water. Do not induce vomiting. Never give anything by mouth to an unconscious person. Call a doctor or Poison Control Center immediately.

               4.2                        Most important symptoms/effects, acute and delayed

no data available

               4.3                        Indication of immediate medical attention and special treatment needed, if necessary

no data available

5.            Fire-fighting measures

               5.1                        Extinguishing media

Suitable extinguishing media

Use dry chemical, carbon dioxide or alcohol-resistant foam.

                5.2                        Specific hazards arising from the chemical

no data available

               5.3                        Special protective actions for fire-fighters

Wear self-contained breathing apparatus for firefighting if necessary.

6.            Accidental release measures

                6.1                        Personal precautions, protective equipment and emergency procedures

Avoid dust formation. Avoid breathing mist, gas or vapours.Avoid contacting with skin and eye. Use personal protective equipment.Wear chemical impermeable gloves. Ensure adequate ventilation.Remove all sources of ignition. Evacuate personnel to safe areas.Keep people away from and upwind of spill/leak.

               6.2                        Environmental precautions

Prevent further spillage or leakage if it is safe to do so. Do not let the chemical enter drains. Discharge into the environment must be avoided.

               6.3                        Methods and materials for containment and cleaning up

Collect and arrange disposal. Keep the chemical in suitable and closed containers for disposal. Remove all sources of ignition. Use spark-proof tools and explosion-proof equipment. Adhered or collected material should be promptly disposed of, in accordance with appropriate laws and regulations.

7.            Handling and storage

               7.1                        Precautions for safe handling

Handling in a well ventilated place.                Wear suitable protective clothing.                Avoid contact with skin and eyes.                Avoid formation of dust and aerosols.                Use non-sparking tools.                Prevent fire caused by electrostatic discharge steam.

               7.2                        Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

8.            Exposure controls/personal protection

               8.1                        Control parameters

Occupational Exposure limit values

no data available

               8.2                        Appropriate engineering controls

Ensure adequate ventilation.                    Handle in accordance with good industrial hygiene and safety practice.                    Set up emergency exits and the risk-elimination area.

8.3            Individual protection measures, such as personal protective equipment (PPE)

Eye/face protection

Wear tightly fitting safety goggles with side-shields conforming to EN 166(EU) or NIOSH (US).

Skin protection

Wear fire/flame resistant and impervious clothing. Handle with gloves. Gloves must be inspected prior to use. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.

Respiratory protection

If the exposure limits are exceeded, irritation or other symptoms are experienced, use a full-face respirator.

Thermal hazards

no data available

9.            Physical and chemical properties

Physical state

white to light yellow crystal powder


no data available


no data available

Melting point/ freezing point


Boiling point or initial boiling point and boiling range



no data available

Lower and upper explosion limit / flammability limit

no data available

Flash point


Auto-ignition temperature

no data available

Decomposition temperature

no data available


no data available

Kinematic viscosity

no data available


no data available

Partition coefficient n-octanol/water

no data available

Vapour pressure

51.5mmHg at 25°C

Density and/or relative density

1.536 g/cm3

Relative vapour density

no data available

Particle characteristics

no data available

10.            Stability and reactivity

               10.1                        Reactivity

no data available

               10.2                        Chemical stability

no data available

               10.3                        Possibility of hazardous reactions

no data available

               10.4                        Conditions to avoid

no data available

               10.5                        Incompatible materials

no data available

               10.6                        Hazardous decomposition products

no data available

11.            Toxicological information

Acute toxicity

  • Oral: no data available

  • Inhalation: no data available

  • Dermal: no data available

Skin corrosion/irritation

no data available

Serious eye damage/irritation

no data available

Respiratory or skin sensitization

no data available

Germ cell mutagenicity

no data available


no data available

Reproductive toxicity

no data available

STOT-single exposure

no data available

STOT-repeated exposure

no data available

Aspiration hazard

no data available

12.            Ecological information

                12.1                        Toxicity

  • Toxicity to fish: no data available

  • Toxicity to daphnia and other aquatic invertebrates: no data available

  • Toxicity to algae: no data available

  • Toxicity to microorganisms: no data available

               12.2                        Persistence and degradability

no data available

               12.3                        Bioaccumulative potential

no data available

               12.4                        Mobility in soil

no data available

               12.5                        Other adverse effects

no data available

13.            Disposal considerations

               13.1                        Disposal methods


The material can be disposed of by removal to                    a licensed chemical destruction plant or by controlled incineration                    with flue gas scrubbing. Do not contaminate water, foodstuffs,                    feed or seed by storage or disposal. Do not discharge to sewer systems.

Contaminated packaging

Containers can be triply rinsed (or equivalent) and                    offered for recycling or reconditioning.                    Alternatively, the packaging can be punctured to                    make it unusable for other purposes and then be disposed of                    in a sanitary landfill. Controlled incineration                    with flue gas scrubbing is possible for combustible packaging materials.

14.            Transport information

                14.1                        UN Number

ADR/RID: Not dangerous goods. (For reference only, please check.)IMDG: Not dangerous goods. (For reference only, please check.)IATA: Not dangerous goods. (For reference only, please check.)

               14.2                        UN Proper Shipping Name

ADR/RID: Not dangerous goods. (For reference only, please check.)IMDG: Not dangerous goods. (For reference only, please check.)IATA: Not dangerous goods. (For reference only, please check.)

               14.3                        Transport hazard class(es)

ADR/RID: Not dangerous goods. (For reference only, please check.)IMDG: Not dangerous goods. (For reference only, please check.)IATA: Not dangerous goods. (For reference only, please check.)

               14.4                        Packing group, if applicable

ADR/RID: Not dangerous goods. (For reference only, please check.)IMDG: Not dangerous goods. (For reference only, please check.)IATA: Not dangerous goods. (For reference only, please check.)

                   14.5                        Environmental hazards


               14.6                        Special precautions for user

no data available

               14.7                        Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code

no data available

15.            Regulatory information

               15.1                        Safety, health and environmental regulations specific for the product in question

Chemical nameCommon names and synonymsCAS numberEC number
2,4,6-Trifluorobenzoic Acid2,4,6-Trifluorobenzoic acid2,4,6-Trifluorobenzoic acid 2,4,6-trifluorobenzoic acid2,4,6-Trifluorobenzoic Acid2,4,6-Trifluorobenzoic acid2,4,6-Trifluorobenzoic acid 2,4,6-trifluorobenzoic acid28314-80-9-
European Inventory of Existing Commercial Chemical Substances (EINECS)Not Listed.
EC InventoryNot Listed.
United States Toxic Substances Control Act (TSCA) InventoryNot Listed.
China Catalog of Hazardous chemicals 2015Not Listed.
New Zealand Inventory of Chemicals (NZIoC)Not Listed.
Philippines Inventory of Chemicals and Chemical Substances                        (PICCS)Not Listed.
Vietnam National Chemical InventoryListed.
Chinese Chemical Inventory of Existing Chemical Substances (China                        IECSC)Listed.
Korea Existing Chemicals List (KECL)Not Listed.

16.            Other information

Information on revision

Creation Date2020-05-04
Revision Date2020-05-04

Abbreviations and acronyms

  • CAS: Chemical Abstracts Service

  • ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road

  • RID: Regulation concerning the International Carriage of Dangerous Goods by Rail

  • IMDG: International Maritime Dangerous Goods

  • IATA: International Air Transportation Association

  • TWA: Time Weighted Average

  • STEL: Short term exposure limit

  • LC50: Lethal Concentration 50%

  • LD50: Lethal Dose 50%

  • EC50: Effective Concentration 50%


  • IPCS - The International Chemical Safety Cards (ICSC), website:          

  • HSDB - Hazardous Substances Data Bank, website:

  • IARC - International Agency for Research on Cancer, website:

  • eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website:          

  • CAMEO Chemicals, website:

  • ChemIDplus, website:

  • ERG - Emergency Response Guidebook by U.S. Department of Transportation, website:          

  • Germany GESTIS-database on hazard substance, website:          

  • ECHA - European Chemicals Agency, website:

Any questions regarding this SDS, Please send your inquiry to

Disclaimer: The above information is believed to be correct but does not purport to be all inclusive and            shall be used only as a guide. The information in this document is based on the present state of our            knowledge and is applicable to the product with regard to appropriate safety precautions. It does not            represent any guarantee of the properties of the product. We as supplier shall not be held liable for any            damage resulting from handling or from contact with the above product.

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