We randomly assigned 870 patients who had resected stage III melanoma with BRAF V600E or V600K mutations to receive 12 months of oral dabrafenib (at a dose of 150 mg twice daily) plus trametinib (2 mg once daily) or two matched placebos.
In this double-blind trial, we randomly assigned 3730 patients with class II, III, or IV heart failure and an ejection fraction of 40% or less to receive empagliflozin (10 mg once daily) or placebo, in addition to recommended therapy. The primary outcome was a composite of cardiovascular death or hospitalization for worsening heart failure.
Alzheimer’s is a progressive brain disease that destroys brain cells, leading to memory loss and impairments in thinking and behavior. These symptoms are severe enough to restrict an individual's daily life and activities.
According to the Centers for Disease Control and Prevention (CDC), Alzheimer’s disease is a type of neurodegenerative illness that, at its mildest, can mean a person has difficulty remembering things. At its most severe, it can result in an almost total inability to respond to the world and other people.
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Shanghai Up-Fluorochem Co., Ltd. (UP-F) . It was founded by Dr. from Shanghai Jiao Tong University and Zhejiang University, with sophisticated technical talents and advanced technology in the international fluorine chemical industry.
UP-F is an innovative modern industrial enterprise engaged in the R&D, production and application of fluorine-containing pharmaceuticals, pesticides and intermediates, fluorine-containing materials and intermediates and organic fluorine-containing blocks and catalysts.
Our company is committed to becoming the world's leading provider of integrated organic fluorine chemical technology solutions. Providing with High-quality fluorine-containing organic compounds for research and development or industrial use for customers who are widely distributed in academia and industry globally is one of our major mission. In addition, we provide comprehensive research and development supporting, such as cooperative development, commissioned development and other scientific research services.
Fluorine chemical technology development, new material product development, chemical technology solutions, and innovative business investment.
UP-F has established project cooperation with a number of university key laboratories and research institutions. And look forward to contributing to the global chemical and new materials technology industry. UP-F sincerely welcomes Chinese and foreign friends to come to conduct business, exchange technology and cooperation opportunities.